infirmity

• This drastic process smoothed their path, but could not completely solve the problem; and the characteristic Tudor infirmity was already apparent in the reign of Henry VII. —  Henry VIII.
• He sympathizes with her infirmity, and with fine self-denial eats as she does. —  How to Eat A Cure for "Nerves"
• This anxiety of man to know the aim and the end is essentially human; it is a kind of infirmity or provincialism of the mind, and has nothing in common with universal reality. —  The Buried Temple
• In the first place he was suddenly freed from his physical infirmity, and shortly after his restoration he met and married the woman who, as long as she lived with him, did all that was possible to make him happy. —  Jerome Cardan A Biographical Study
• None of the degrading signs of his infirmity were lacking; and she saw at once that, while in the early days of the habit he had probably mixed his drugs, so that the conflicting symptoms neutralized each other, he had now sunk into open morphia-taking. —  The Fruit of the Tree

Roget's II: The New Thesaurus

Used in the Same Context