malady

• As Professor Frary notes, one of the signal presenting features of this malady is the suddenness of its onset. —  Knox
• For it is to be noted that hardly any one who suffers from this malady is aware of it. —  To Infidelity and Back
• In some cases, when this state of the malady is attained, the patient can no longer exercise himself by walking in his usual manner, but is thrown on the toes and forepart of the feet; being, at the same time, irresistibly impelled to take much quicker and shorter steps, and thereby to adopt unwillingly a running pace. —  An Essay on the Shaking Palsy
• The prevalence of the disease on the same damp soils which produce ague in man and anthrax in cattle has been quoted in support of this doctrine, as also the fact that, other things being equal, the malady is always more prevalent in basins surrounded by hills where the air is still and such products are concentrated, and that a forest or simple belt of trees will, as in ague, at times limit the area of its prevalence. —  Special Report on Diseases of the Horse
• She was briefly told, in reply, that the malady was hereditary, and the fits not occurring but at very long and irregular intervals, she must be carefully watched; for the length of these lucid periods only rendered her more mischievous, when any vexation or caprice brought on the paroxysm of phrensy Had her master trusted her, it is probable that neither pity nor curiosity would have made her swerve from the straight line of her interest; for she had suffered too much in her intercourse with mankind, not to determine to look for support, rather to humouring their passions, than courting their approbation by the integrity of her conduct. —  Posthumous Works of the Author of A Vindication of the Rights of Woman

Roget's II: The New Thesaurus

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