from The American Heritage® Dictionary of the English Language, 4th Edition
- n. A drug used in the treatment of cardiovascular diseases, such as hypertension and congestive heart failure, that functions by inhibiting the enzymes that activate angiotensin.
from Wiktionary, Creative Commons Attribution/Share-Alike License
- n. An ACE inhibitor used to treat hypertension and some types of congestive heart failure.
from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.
- n. a drug (trade name Capoten) that blocks the formation of angiotensin in the kidneys resulting in vasodilation; used in the treatment of hypertension and congestive heart failure
For their study, they gave a short-acting ACE inhibitor, called captopril brand name Capoten, at different times of day to laboratory mice with high blood pressure.
ACE inhibitors such as captopril taken orally are often used to treat hypertension, but according to Emanuele there is evidence that applied topically they can help treat some skin disorders such as keloids
The one exception: Combining a potassium-retaining diuretic and an ACE inhibitor, such as benazepril (generic, Lotensin), captopril (generic, Capoten), or enalapril (generic, Vasotec), can cause worrisome potassium accumulation even in people with healthy kidneys.
The idea of using snake venom to treat heart disease may seem strange, yet that is exactly what Bristol-Myers Squibb did when they used the venom of a pit viper, Bothrops jararaca, to develop Capoten (captopril).
In the 1970s, the Squibb pharmaceutical company used venom from the Brazilian arrowhead viper to help develop captopril, used to treat hypertension and congestive heart failure, without payment of the royalties Brazilians think are due them.
To test that hypothesis, Larry Grupp and associates at the University of Toronto used captopril and enalapril on rats, and found that these anti-hypertensive drugs significantly reduced their alcohol intake.
Dr. Sole said it may be better to use a short-acting medication, like captopril, at night when the heart is in "repair mode" particularly in patients who find it hard to tolerate the side effects.
These widely used drugs such as captopril, lisinopril and enalapril are well-known causes of a cough.
Patients should notify their doctor if taking quinidine, captopril, or enalopril, or if they are sensitive to iodine, or suffer from dermatitis herpetiformis, thyrotoxicosis or kidney problems before taking potassium iodate or any thyroid blocker.
The following medicines were included: atenolol, captopril, hydrochlorothiazide, losartan and nifedipine.
Wordnik is becoming a not-for-profit! Read our announcement here.