cataplexy

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The researchers discovered that in addition to unique HLA variants, people with narcolepsy-cataplexy are also more likely to have unique variants of the TCRA gene, which encodes a receptor protein on the surface of T cells.

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Definitions (3)

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  1. noun A sudden loss of muscle tone and strength, usually caused by an extreme emotional stimulus.

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Examples

  • The researchers discovered that in addition to unique HLA variants, people with narcolepsy-cataplexy are also more likely to have unique variants of the TCRA gene, which encodes a receptor protein on the surface of T cells. —  EurekAlert! - Breaking News
  • In people with the HLA variants that predispose to narcolepsy-cataplexy, there is about a 20-fold higher frequency of the disorder if variants in the TCRA gene are present. —  EurekAlert! - Breaking News
 

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Etymologies (2)

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  1. From Greek kataplēxis, fixation (of the eyes), from kataplēssein, to astound, terrify : kata-, intensive pref.; see cata- + plēssein, plēk-, to strike; see plāk-2 in Indo-European roots.

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  1. = French cataplexie = Spanish Portuguese cataplexia, from New Latin *cataplexia, from Greek καταπλήξ, stricken, struck (cf. κατάπληξις, consternation), from καταπλήσσ, σ1ιν, strike down, from κατά, down, + πλήσσ, σ1ειν, (√ *πληγ, *πλαγ), strike: see plectrum, plague.
 

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/ˈkætəplɛksi/
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