cataplexy

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The researchers discovered that in addition to unique HLA variants, people with narcolepsy-cataplexy are also more likely to have unique variants of the TCRA gene, which encodes a receptor protein on the surface of T cells.

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Definitions (3)

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  1. noun A sudden loss of muscle tone and strength, usually caused by an extreme emotional stimulus.

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Examples (21)

  • At the other end of the symptomatic spectrum is cataplexy, periods of weakness brought on by excitement or heightened emotion. —  Omni: August 1994
  • Sleep paralysis is a condition that may occur in normal subjects or be associated with narcolepsy, cataplexy, and hypnagogic hallucinations. —  Yahoo! Answers: Latest Questions
  • These neurons are active in the waking state and turn off during sleep and in their absence, animals and humans experience narcolepsy with cataplexy or sudden loss of mucle tone. —  Signs of the Times
  • About 1 in 2,000 Americans have narcolepsy-cataplexy. —  EurekAlert! - Breaking News
  • Genetic and environmental factors both clearly play a role in narcolepsy-cataplexy. —  EurekAlert! - Breaking News
 

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Etymologies (2)

Toggle American Heritage etymologies American Heritage Dictionary (1)

  1. From Greek kataplēxis, fixation (of the eyes), from kataplēssein, to astound, terrify : kata-, intensive pref.; see cata- + plēssein, plēk-, to strike; see plāk-2 in Indo-European roots.

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  1. = French cataplexie = Spanish Portuguese cataplexia, from New Latin *cataplexia, from Greek καταπλήξ, stricken, struck (cf. κατάπληξις, consternation), from καταπλήσσ, σ1ιν, strike down, from κατά, down, + πλήσσ, σ1ειν, (√ *πληγ, *πλαγ), strike: see plectrum, plague.
 

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/ˈkætəplɛksi/
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