from The American Heritage® Dictionary of the English Language, 4th Edition
- n. A benzodiazepine drug, C16H14ClN3O, whose hydrochloride is used as an antianxiety drug and in the treatment of chronic alcoholism and alcohol withdrawal.
from Wiktionary, Creative Commons Attribution/Share-Alike License
- n. A benzodiazepine derivative used as a sedative drug.
from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.
- n. a tranquilizer (trade names Librium and Libritabs) used in the treatment of alcoholism
One of those packages was sent to Alves in Marlborough, and after the box was inspected by FDA special agents, they found hundreds of capsules containing substances such as chlordiazepoxide, an active ingredient in an anti-anxiety drug; fenproporex, a stimulant that is converted in the body to amphetamine; and fluoxetine, an antidepressant.
According to the FDA press release, chlordiazepoxide may be habit forming and can cause dizziness and drowsiness, and fluoxetine has been linked to several serious drug interactions and to even the possibility of promoting suicide in its takers.
Administration of IM chlordiazepoxide 25 mg IM, t.i.d. and then q.i.d. had little effect.
Initial emergency treatment may require restraints and then the administration of small amounts of IV anxiolytics chlordiazepoxide, 10-25 mg, or diazepam, 5-10 mg.
Substantial dosages may be required to inhibit a panic attack e.g., 15-20 mg of diazepam or 25-50 mg of chlordiazepoxide, but doses rarely have to be repeated in a single day because of the long half-life of these drugs.
These patients often respond rapidly to IV or oral long-acting anxiolytics, such as chlordiazepoxide or diazepam doses of 25 mg or 10 mg, respectively and can return home the same day.
The drugs of choice are triazolam in the short-acting subgroup; lorazepam in the intermediate-acting subgroup; and in the long-acting subgroup, chlordiazepoxide or diazepam for withdrawal states and diazepam for everything else.
When the hyperventilation syndrome has been resolved, additional anxiety symptoms can be controlled by chlordiazepoxide or diazepam in oral doses 25 mg or 10 mg, respectively.
A typical regimen with chlordiazepoxide is to give 100 mg IV and to repeat this dose every 4 to 6 hours during the first 24-hour period.
If the possibility of grand mal seizure is high, the patient will also be sedated with chlordiazepoxide Librium, a tranquilizer, until the withdrawal symptoms subside.
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