from The American Heritage® Dictionary of the English Language, 4th Edition
- n. See vitamin B12.
from Wiktionary, Creative Commons Attribution/Share-Alike License
- n. Any of several substances depending on the upper axial ligand of the cobalt ion.
from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.
- n. a B vitamin that is used to treat pernicious anemia
Aminoacidopathies (maple syrup urine disease; homocystinuria; cobalamin deficiencies; tyrosinemia; urea cycle defects (ornithine transcarbamylase, carbamyl phosphate synthase, citrullinemia, argininosuccinic aciduria, arginase deficiencies) and non-ketotic hyperglycinemia)
The publications advocate use of the assay to identify a need for cobalamin/folate supplements.
These publications state that elevated total homocysteine correlates to cobalamin/folate deficiency and that this deficiency can be treated with vitamin supplements.
I take a B-100 supplement with 400 mcg of folic acid and 100 mcg of B12 as cobalamin.
A method for detecting a deficiency of cobalamin or folate in warm-blooded animals comprising the steps of:
In terms of this structure, one can begin to understand some of the uses to which the cobalamin nucleus is put in nature, for example, its part in the transfer of methyl groups.
Again the intensities of the X-ray diffraction spectra were measured, Patterson and electron-density distributions were calculated, atoms belonging to the best known parts of the cobalamin molecule being placed first in the calculations.
There followed directly an explanation of the observed great instability of the molecule to light and cyanide ions -- instability which had led to the failure of earlier investigations to recognise its existence and to isolate, in its place, cyano-cobalamin.
Cobyric acid is the natural precursor of the most remarkable molecule of our series, Co-5'-deoxyadenosyl-cobalamin, the coenzyme discovered by Baker, which ought, most properly, to be called vitamin B12.
In addition, the Company is developing earlier stage compounds in its pipeline and has an oral cobalamin nanopolymer drug delivery technology, which has demonstrated positive results for the delivery of insulin by mouth in preclinical animal models.
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