American Heritage® Dictionary of the English Language, Fourth Edition
- n. An immunosuppressive drug obtained from certain soil fungi, used mainly to prevent the rejection of transplanted organs.
“Belatacept is different from calcineurin inhibitors (CNI), such as cyclosporine, which is the class of drugs most commonly used to suppress the immune system in transplant patients, because it does not cause the toxicities associated with CNI - such as nephrotoxicity and aggravating cardiovascular risk factors.”
“NOTA is the result of a wonder-drug called cyclosporine a protein found in a Norwegian soil fungus that can prevent the immune system from attacking a donated organ as a foreign invader such as bacteria.”
“It makes it possible to use less of a generic drug called cyclosporine, which thus reduces cyclosporine-related side effects.”
“Clinical research, meanwhile, showed that a particular immunosuppressant that inhibits NFATc1, a drug called cyclosporine A, has a rather unsightly side effect: excessive hair growth.”
“Echinacea might also interact with drugs that suppress the immune system, such as cyclosporine (Sandimmune and generic).”
“Echinacea might also interact with drugs that suppress the immune system, such as cyclosporine Sandimmune and generic.”
“Most panelists noted that belatacept was not quite as effective as current treatments such as cyclosporine, a type of calcineurin inhibitor (CNIs) sold as Abbott Laboratories 'Gengraf and Novartis's Sandimmune and Neoral.”
“Calcineurin inhibitors (CNI) such as cyclosporine (CsA) or tacrolimus (TAC) are the cornerstone of immunosuppressive treatment after transplantation.”
“Many patients also have great success treating the scalp with UV light therapy, and systemic medications such as cyclosporine work better for some people than topical medications.”
“It was only after the invention of the heart - lung machine, coupled with the development of immunosuppressive drugs such as cyclosporine, that organs such as the lungs could be transplanted with a reasonable chance of patient recovery.”
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