Definitions

from The American Heritage® Dictionary of the English Language, 5th Edition.

  • noun An immunosuppressive drug obtained from certain soil fungi, used mainly to prevent the rejection of transplanted organs.

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun A cyclic oligopeptide, obtained from soil fungi, used as an immunosuppressive drug after an organ transplant.

Etymologies

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Examples

  • Belatacept is different from calcineurin inhibitors (CNI), such as cyclosporine, which is the class of drugs most commonly used to suppress the immune system in transplant patients, because it does not cause the toxicities associated with CNI - such as nephrotoxicity and aggravating cardiovascular risk factors.

    EurekAlert! - Breaking News 2010

  • Belatacept is different from calcineurin inhibitors (CNI), such as cyclosporine, which is the class of drugs most commonly used to suppress the immune system in transplant patients, because it does not cause the toxicities associated with CNI - such as nephrotoxicity and aggravating cardiovascular risk factors.

    Medlogs - Recent stories 2010

  • NOTA is the result of a wonder-drug called cyclosporine a protein found in a Norwegian soil fungus that can prevent the immune system from attacking a donated organ as a foreign invader such as bacteria.

    The Volokh Conspiracy » IJ’s Bone Marrow Case: History of NOTA 2009

  • It makes it possible to use less of a generic drug called cyclosporine, which thus reduces cyclosporine-related side effects.

    The Money Times Brian Orelli 2010

  • Clinical research, meanwhile, showed that a particular immunosuppressant that inhibits NFATc1, a drug called cyclosporine A, has a rather unsightly side effect: excessive hair growth.

    Biosingularity 2008

  • Echinacea might also interact with drugs that suppress the immune system, such as cyclosporine (Sandimmune and generic).

    Herbal hay fever remedies to watch out for 2008

  • Echinacea might also interact with drugs that suppress the immune system, such as cyclosporine Sandimmune and generic.

    Herbal hay fever remedies to watch out for 2008

  • Most panelists noted that belatacept was not quite as effective as current treatments such as cyclosporine, a type of calcineurin inhibitor (CNIs) sold as Abbott Laboratories 'Gengraf and Novartis's Sandimmune and Neoral.

    Reuters: Top News 2010

  • Calcineurin inhibitors (CNI) such as cyclosporine (CsA) or tacrolimus (TAC) are the cornerstone of immunosuppressive treatment after transplantation.

    PhysOrg.com - latest science and technology news stories 2010

  • Many patients also have great success treating the scalp with UV light therapy, and systemic medications such as cyclosporine work better for some people than topical medications.

    Yahoo! News: Business - Opinion 2010

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