Definitions

from The American Heritage® Dictionary of the English Language, 5th Edition.

  • noun A tricyclic antidepressant, C18H22N2, given in its hydrochloride form that selectively blocks reuptake of norepinephrine.

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun A tricyclic, heterocyclic drug used to treat depression.

from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.

  • noun a tricyclic antidepressant drug that activates the psychomotor system

Etymologies

from The American Heritage® Dictionary of the English Language, 4th Edition

[desmethyl (des- variant of de– + methyl) + (im)ipramine.]

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Examples

  • A recent clinical trial found that one antidepressant, called desipramine Norpramin, and lidocaine -- used either alone or together -- appeared no better than inactive placebo pills and ointments.

    Reuters: Press Release 2011

  • Tricyclic antidepressants, such as desipramine, are inexpensive, work as well as more expensive antidepressants, and are a mainstay of treatment.

    STLtoday.com Top News Headlines 2009

  • "In people, the cortisol level is corrected by drugs such as desipramine, and so it is in our mice.

    PhysOrg.com - latest science and technology news stories 2010

  • "In people, the cortisol level is corrected by drugs such as desipramine, and so it is in our mice.

    Penn State Science kov100 2010

  • "In people, the cortisol level is corrected by drugs such as desipramine, and so it is in our mice.

    Penn State Live 2010

  • "In people, the cortisol level is corrected by drugs such as desipramine, and so it is in our mice.

    R&D Mag - News 2010

  • "In people, the cortisol level is corrected by drugs such as desipramine, and so it is in our mice.

    Penn State Live 2010

  • And when cognitive behavioral therapy was compared with the antidepressant desipramine, the two treatments were equally effective.

    Digestion: Soothing A Sensitive Gut 2008

  • In one of several small U.S. studies, researchers at the University of California, Irvine, gave 17 severely depressed patients a four-week course of SAMe (1,600 mg daily) or desipramine, a well-established antidepressant.

    What Is Same 2008

  • The SAMe recipients enjoyed a slightly higher response rate (62 percent) than the folks on desipramine (50 percent).

    What Is Same 2008

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