“All estrogen products are chemically synthesized, primarily from an active ingredient called diosgenin, a molecule extracted from the tubers and flowers of various plants including Dioscorea, a wild yam.”
“In the 1950s, barbasco was heavily harvested for diosgenin, which is an ingredient of contraceptive products.”
“After having his proposals for the large-scale production of human steroids from diosgenin turned down by U.S. pharmaceutical companies, Marker moved to Mexico and began his own, home-based, small scale production.”
“At Syntex, Djerassi set out to see if diosgenin could be made to yield other steroids, which do not actually exist in nature, but which retain the biological activities of progesterone and are also orally active.”
“Marker had published various studies on diosgenin, a saponin isolated from a Mexican yam species of the genus Dioscorea, and had discovered how to synthesize the human hormone testosterone and progesterone from diosgenin.”
“Fenugreek tea contains diosgenin, a semi-synthetic form of the female sex hormone estrogen and, when prepared as a special tea, is used for natural breast enlargement.”
“He really hoped Monsanto would commercialize his steroid synthesis, but the Mexican yam with its high content of diosgenin eventually killed our effort.”
“Progesterone and orally active progesterone analogues can be readily produced from diosgenin through chemical synthesis and cortisone and other useful corticosteroid hormones by microbial synthesis.”
“A recent discussion paper published by FAO suggests that diosgenin could be produced in the Sudan from the fruits of Balanites aegyptiaca.”
“Studies on diosgenin content in fruits of Balanites roxburghii.”
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