epitope

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This epitope is different from the binding sites targeted by other CD20 antibodies currently available.

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Definitions (2)

Toggle American Heritage definitions American Heritage Dictionary (1)

  1. noun A localized region on the surface of an antigen that is capable of eliciting an immune response and of combining with a specific antibody to counter that response.

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Examples (32)

  • This β2-α2 loop and helix α3 form a solvent-accessible contiguous epitope, which has been proposed to be the recognition area for a hypothetical chaperone, the "protein X". —  CiteULike: Everyone's library
  • L6 muscle cells expressing GLUT4 tagged on an extracellular domain with a Myc epitope (GLUT4myc) were used to assess the functional insertion of GLUT4 into the plasma membrane. —  CiteULike: Everyone's library
  • Studies using epitope-tagged receptors expressed in cultured striatal neurons and a neuroblastoma cell model indicated that this heterologous regulation is mediated by NK1R-dependent sequestration of arrestins on endosome membranes. —  CiteULike: Everyone's library
  • Genetic mechanisms that control disease susceptibility are mainly represented by association between RA and the shared epitope (a specific amino acid sequence on DR4) (29). —  Recently Uploaded Slideshows
  • This method works well for an antibody recognizing a linear epitope, but not for that recognizing a discontinuous epitope. —  CiteULike: Everyone's library
 

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