galantamine

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Peripheral administration of the acetylcholinesterase inhibitor galantamine significantly reduced serum TNF levels through vagus nerve signaling, and protected against lethality during murine endotoxemia.

Examples (5)

  • Peripheral administration of the acetylcholinesterase inhibitor galantamine significantly reduced serum TNF levels through vagus nerve signaling, and protected against lethality during murine endotoxemia. —  CiteULike: Everyone's library
  • Administration of a centrally-acting muscarinic receptor antagonist abolished the suppression of TNF by galantamine, indicating that suppressing acetylcholinesterase activity, coupled with central muscarinic receptors, controls peripheral cytokine responses. —  CiteULike: Everyone's library
  • Administration of galantamine to alpha7nAChR knockout mice failed to suppress TNF levels, indicating that the alpha7nAChR-mediated cholinergic anti-inflammatory pathway is required for the anti-inflammatory effect of galantamine. —  CiteULike: Everyone's library
  • Available cholinesterase inhibitors drugs are donepezil, galantamine, rivastigmine, and tacrine. antipsychotic agents (olanzapine, quetiapine, risperidone), were found to have "adverse effects offset advantages in the efficacy of atypical antipsychotic drugs for the treatment of psychosis, aggression, or agitation in patients with Alzheimer's disease." —  Citizendium, the Citizens' Compendium - Recent changes [en]
  • Reminyl (galantamine) Co-developed by Shire Pharmaceuticals and the Janssen Research Foundation 4. —  Recently Uploaded Slideshows
 

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