Definitions
American Heritage® Dictionary of the English Language, Fourth Edition
- n. A disease caused by the inhalation of spores of the fungus Histoplasma capsulatum, most often asymptomatic but occasionally producing acute pneumonia or an influenzalike illness and spreading to other organs and systems in the body.
Wiktionary
- n. pathology A lung disease caused by a fungus, Histoplasma capsulatum, often asymptomatic otherwise with symptoms similar to those of flu.
Examples
“Dr. Jeffrey Siegel of the U.S. Food and Drug Administration said the agency recently became concerned when 240 cases of a fungal infection called histoplasmosis surfaced in people taking the arthritis drugs, resulting in 45 deaths.”
FDA-Approved Arthritis Drugs Could Lead to Fatal Fungal Infections
“Use of Cimzia, Enbrel Humira and Remicade may put patients at risk for deadly fungal infections such as histoplasmosis, blastomycosis, and coccidioidomycosis (San Joaquin Valley Fever). disease that seeks out the patient's lungs as primary target for its workings, has been known since 1905 as Darling's disease.”
“How did it become a blockbuster even though such drugs which include Remicade, Enbrel and Cimzia and are called TNF blockers are linked to TB, rare cancers and lethal infections like histoplasmosis?”
The Huffington Post: Martha Rosenberg: Blockbuster Drug Causes Cancer, TB and Lethal Infections
“You really don't understand pneumonia (and probably can't treat it very well) until you understand how different the disease caused by influenza virus is from the one caused by the tuberculosis bacterium or the histoplasmosis fungus.”
The Washington Post: War against cancer has more than one target
“Eleven years ago, Nicole was diagnosed with ocular histoplasmosis and became blind in one eye, and, like me, she developed macular degeneration.”
The Huffington Post: Jim Gibbons: People Who Are Blind Must Have Visions of Greatness
“The first thing I remember about Earth day were reports of some cases of histoplasmosis in a group of well meaning well-meaners who breathed in a bunch of fungal spores when they set out to clean up their little portions of the earth.”
“Patients who take any of the four arthritis drugs and exhibit any signs of histoplasmosis, including persistent fever, cough, shortness of breath or fatigue, are urged to call their doctor.”
FDA-Approved Arthritis Drugs Could Lead to Fatal Fungal Infections
“The FDA hasissued a warning about histoplasmosis to healthcare professionals on its Web site, noting that the infection is not “consistently recognized” in patients taking the drugs.”
FDA-Approved Arthritis Drugs Could Lead to Fatal Fungal Infections
“The raspy-voiced icon was hospitalized, said a spokesman for Columbia Records, with an illness called histoplasmosis.”
“The FDA will require all four products to have "more uniform" boxed warnings about fungal infections that will highlight histoplasmosis, as well as ask doctors to better identify patients at high risk for fungal infections and consider starting those patients on a course of antifungal therapy even before the condition is diagnosed, said the FDA's Dr. Siegel.”
The Wall Street Journal: Tougher Warnings Ordered on Four Drugs
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vanishedone Scientific American: 'Now drug regulators say a class of medicines called TNF alpha blockers such as Enbrel, Remicade, Humira and Cimzia must carry stronger warnings that they pose a serious risk of histoplasmosis infection, a respiratory or blood illness caused by fungi endemic to the Midwest.' Sep 6, 2008