Definitions

from The American HeritageĀ® Dictionary of the English Language, 4th Edition

  • n. An isoenzyme.

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. An isoenzyme.

Etymologies

iso- + (en)zyme.
(American Heritage® Dictionary of the English Language, Fourth Edition)

Examples

  • The findings add to an accumulation of evidence suggesting that inhibition of the cytochrome P450 2D6 isozyme (CYP2D6) may adversely affect outcomes in breast cancer patients taking tamoxifen.

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  • Click on an or generic/brand variant to breath for judgement about the isozyme in our database.

    Wii-volution

  • -- (BUSINESS WIRE) -- Apr 8, 2009 - KAI Pharmaceuticals, Inc., a privately held drug discovery and development company, today announced the Company has initiated a third Phase 2a study of KAI-1678, a first-in-class, isozyme-selective, small peptide inhibitor of the epsilon protein kinase C pathway (epsilon PKC).

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  • Lindsley CW, Zhao Z, Leister WH, Robinson RG, Barnett SF, et al. (2005) Allosteric Akt (PKB) inhibitors: discovery and SAR of isozyme selective inhibitors.

    PLoS Biology: New Articles

  • Liao YF, Kudo S, Eto S, Mattei MG, et al. (1995) Molecular cloning and expression of cDNAs encoding human alpha-mannosidase II and a previously unrecognized alpha-mannosidase IIx isozyme.

    PLoS ONE Alerts: New Articles

  • Fox EA, Strydom DJ, Riordan JF (1989) Molecular cloning of human testicular angiotensin-converting enzyme: the testis isozyme is identical to the C-terminal half of endothelial ACE.

    PLoS ONE Alerts: New Articles

  • NSAIDs may reduce pain and inflammation following injury by inhibiting COX isozyme-induced prostaglandin synthesis; however, as they circulate within the body indiscriminately, rather than localizing to the source of an athlete's specific aches and pains, they may produce undesirable side effects.

    Health News from Medical News Today

  • Our results suggest that low CYP 2C isozyme activity is a common property of drugs, whereas other isozymes, such as CYP 2D6, show little discrimination between drugs and unoptimized compounds found in screening libraries.

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  • We observed cross-library isozyme inhibition (30-78%) with important differences between libraries.

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  • Tramadol undergoes hepatic metabolism via the cytochrome P450 isozyme CYP2D6, being O - and N-demethylated to five different metabolites.

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  • are enzymes that differ in amino acid sequence but catalyze the same chemical reaction

    February 18, 2011