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  1. mercaptopurine love

Definitions

American Heritage® Dictionary of the English Language, Fourth Edition

  1. n. A purine analogue, C5H4N4S, that acts as an antimetabolite by interfering with purine synthesis, used primarily in the treatment of acute leukemia.

Wiktionary

  1. n. A particular oral drug used in the treatment of cancer.

WordNet 3.0

  1. n. a drug (trade name Purinethol) that interferes with the metabolism of purine and is used to treat acute lymphocytic leukemia

Examples

  • “When a 12-year-old boy from Illinois with ALL arrived at St. Jude in 2001, Pui administered everything but the kitchen sink: the drugs prednisone, vincristine, daunorubicin, and asparaginase, followed by cyclophosphamide, cytarabine, and mercaptopurine.”

    Newsweek: Curing Cancer

  • “Six weeks later, he gave the boy four courses of high-dose methotrexate, daily mercaptopurine, and four triple-drug treatments into the spinal fluid.”

    Newsweek: Curing Cancer

  • “The next regimen they would try would be a combination of all four drugs: vincristine, amethopterin, mercaptopurine, and prednisone.”

    Simon & Schuster: The Emperor of All Maladies

  • “Most can handle standard doses of the drug mercaptopurine.”

    Newsweek: A Revolution In Medicine

  • “The result was azathioprine (1957) which replaced mercaptopurine as an inhibitor of the immune response.”

    Physiology or Medicine 1988 - Press Release

  • “However, studies with a 6-mercaptopurine-resistant strain of L. casei revealed the 6-MP was unable to utilize hypoxanthine for growth (29).”

    Nobel Lecture The Purine Path To Chemotherapy

  • “The liposomal ld50 of mercaptopurine was compared to fold 480 mg/kg in the and 425 mg/kg in the rat.”

    Wii-volution

  • “The intramuscular ld50 of mercaptopurine was licensed to suffer 480 mg/kg in the what is allopurinol for and 425 mg/kg in the rat.”

    Wii-volution

  • “This is the polygonally from uninformative carpeting diestrual bawdy rococo handcar premium mercaptopurine.”

    Rational Review

  • “Genetic tests are used to determine whether certain drugs are prescribed, and in what dose, for HIV-AIDS (the drug abacavir), psychosis (clozapine), blood thinning (warfarin), the heart condition called long QT syndrome (beta blockers) and cancer (imatinib, irinotecan, 5-fluorouracil, mercaptopurine, or tamoxifen).”

    Newsweek: The Genome Generation

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‘mercaptopurine’ has been looked up 341 times, added to 3 lists, and has a Scrabble score of 22.