from The American Heritage® Dictionary of the English Language, 4th Edition
- n. A toxic antimetabolite, C20H22N8O5, that acts as a folic acid antagonist to interfere with cellular reproduction and is used in the treatment of psoriasis, certain cancers, and certain inflammatory diseases such as rheumatoid arthritis.
from Wiktionary, Creative Commons Attribution/Share-Alike License
- n. An antimetabolite and antifolate drug used in treatment of cancer and autoimmune diseases.
from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.
- n. toxic antimetabolite that limits cellular reproduction by acting as an antagonist to folic acid; used to treat certain cancers and psoriasis and rheumatoid arthritis
methotre- (probably shortening and alteration of methylaminopterin, one of its chemical names : methyl + aminopterin) + perhaps (o)x(y)- + -ate2.(American Heritage® Dictionary of the English Language, Fourth Edition)