American Heritage® Dictionary of the English Language, Fourth Edition
- n. An enzyme in the cells of most tissues that catalyzes the oxidation of monoamines such as norepinephrine and serotonin.
- n. biochemistry Either of two enzymes, found in the outer membrane of mitochondria, that degrade biogenic amines and are thus responsible for the destruction of transmitter substances at neuronal synapses.
- n. an enzyme that catalyzes the oxidation of many body compounds (e.g., epinephrine and norepinephrine and serotonin)
“The data showed that Cloninger’s Type II alcoholics—those with a high rate of heritability—have a low level of monoamine oxidase activity.”
“In computer analysis of both monoamine oxidase and adenylate cyclase in all the blood samples, the experimenters were able to identify 75 percent of the subjects who were alcoholic, and 73 percent of those who were not alcoholic.”
“For example, monoamine oxidase prevents an oversupply of the neurotransmitter norepinephrine by converting it into a nonactive compound.”
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