Definitions

from The American Heritage® Dictionary of the English Language, 4th Edition

  • adj. Of, forming, or derived from a single clone: a monoclonal population of tumor cells.
  • n. A monoclonal product, especially a monoclonal antibody.

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • adj. genetically engineered from a single clone; used especially of a protein or antibody
  • n. something produced from a single clone, especially a monoclonal antibody

from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.

  • adj. forming or derived from a single clone
  • n. any of a class of antibodies produced in the laboratory by a single clone of cells or a cell line and consisting of identical antibody molecules

Etymologies

mono- + clone + -al (Wiktionary)

Examples

  • RABER: A number of new drugs have come along that are what we call monoclonal antibodies.

    CNN Transcript Aug 13, 2005

  • Standard methods were available for selectively growing cells with functional HPRT enzymes and had already been used for several years for selection of mutants, hybridoma cells in monoclonal antibody production etc.

    The 2007 Nobel Prize in Physiology or Medicine - Advanced Information

  • Dutch researchers conducted the study because there has been evidence that people can develop immune resistance to drugs known as monoclonal antibodies, which are derived from living cells.

    Study Finds Immune Resistance to Abbott's Humira in Some Patients

  • Michael Emery, a 68-year-old retired engineer in Bonita Springs, Fla., says his doctor gave him a free one-month subscription to help him learn more about his rare condition called monoclonal gammopathy of undetermined significance, or MGUS.

    Online Records Get Patients Involved in Care

  • MabThera belongs to a group of biological therapies, known as monoclonal antibodies.

    Roche Drug Slows Leukemia

  • A blood test can detect pregnancy six to eight days after ovulation.6 Both tests, known as monoclonal antibody tests, detect human chorionic gonadotropin hCG, a hormone present first in the bloodstream and then in urine during pregnancy.

    OUR BODIES, OURSELVES

  • Bristol-Myers Squibb in New York, is a so-called monoclonal antibody.

    The Washington Post: National, World & D.C. Area News and Headlines - washingtonpost.com

  • Yusuf Hamied plans to invest in companies in India and Hong Kong that make so-called monoclonal antibodies.

    Bloomberg

  • The team, led by Lawren Wu, generated a therapeutic molecule known as a monoclonal antibody that targets the portion of human IgE that is contained in IgE molecules on the surface of B cells but not in IgE molecules in the blood.

    PhysOrg.com - latest science and technology news stories

  • He said his team is now working to develop either a pill that people could take to block the effects of these natural "heat messengers," or engineered immune system proteins called monoclonal antibodies that could be infused to mop them up.

    canada.com Top Stories

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