The ONGLYZA application to the FDA includes use as a monotherapy, as an adjunct to diet and exercise, use in combination with three types of commonly used oral anti-diabetic (OAD) medications - metformin, thiazolidinediones and sulfonylureas (SUs) when the single agent alone does not provide adequate glycemic control, as an adjunct to diet and exercise - and use in initial combination therapy with metformin, as an adjunct to diet and exercise.— Medlogs - Recent stories
"Previous preclinical data indicates that reovirus tends to localize in the lungs, and we have seen clinical responses in metastatic lung lesions with REOLYSIN as a monotherapy or in combination with paclitaxel and carboplatin," said Dr. Brad Thompson, President and CEO of Oncolytics.— Health News from Medical News Today
The most common adverse events (greater than or equal to 20\%) of Xeloda monotherapy were diarrhea, nausea, stomatitis and hand-foot syndrome.— BioSpace.com Featured News and Stories
Currently, IFNs are relevant in the clinical treatment of a number of solid tumors and hematological malignancies either as a monotherapy or as an adjuvant to chemotherapy of radiotherapy.— GEN News Highlights
In these studies, NGX-4010 could be administered either as a monotherapy or in combination with other systemic neuropathic pain medications.— Health News from Medical News Today

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