from The American Heritage® Dictionary of the English Language, 4th Edition
- n. A condition in which tissues of genetically different types occur in the same organism.
from Wiktionary, Creative Commons Attribution/Share-Alike License
- n. the condition in which more than one genetically distinct population of cells coexist within one individual
from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.
- n. the condition in which an organism has two or more cell populations that differ in genetic makeup
Gonadal mosaicism is a rare event, but it does occur.
Here, a single-cell-level investigation of CNV in different human tissues led us to uncover the phenomenon of mitotically derived genomic mosaicism, which is stable in different cell types of one individual.
Then, when Casey's eye starts to turn blue, she discovers that she's suffering from genetic mosaicism, meaning she was going to be a twin but the other fetus didn't survive the full term.
When a subset of cells contains the same gene mutation or deletion like this, it's called to as gonadal mosaicism.
In addition, we can detect mosaicism as low as 5 to 20% (varying with the meiotic or mitotic origin of the mosaicism).
Recurrent 22q11. 2 deletion in a sibship suggestive of parental germline mosaicism in velocardiofacial syndrome.
In 1 case, a Polish sprinter with an apparent chromosomal mosaicism was stripped of her medals.
Another possibility that could account for a disconnect between genetics and appearance is mosaicism, in which the individual has more than one set of genes, in some cases, some cells could be XX and others XY.
The answer appears to be that the single cell extracted from each embryo could be genetically slightly different from the others, and therefore not representative of the overall embryo, a condition known as mosaicism.
Somatic mosaicism might produce eyes with two different eye colors (i.e. brown and green).
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