- myelo- + dysplasia (Wiktionary)
“Unlike Frei, though, Canellos had turned from advocate to adversary of megadose chemo regimens, in part because he had been among the first to notice a devastating long-term side effect: as doses escalated, some chemotherapeutic drugs damaged the marrow so severely that, in time, these regimens could precipitate a premalignant syndrome called myelodysplasia, a condition that tended to progress to leukemia.”
“Working with mice with normal blood stem cells, Scadden, who is also co-chair of Harvard's inter-School Department of Stem Cell and Regenerative Biology (SCRB), and his team found that when they made a particular genetic alteration in the bone cells surrounding the blood stem cells of the mice, the mice developed a condition called myelodysplasia, a blood disease that is often a precursor of acute myelogenous leukemia (AML), a highly aggressive, usually fatal, form of cancer.”
“Sontag, having survived uterine and breast cancer, had been diagnosed with myelodysplasia, a precancerous disease that often sours into full-blown leukemia.”
“The agency also wants to eliminate its use in myelodysplasia, a form of leukemia.”
“Perhaps myelodysplasia should be taken off the list.”
“Morton began praying for Sagan after he was diagnosed with myelodysplasia, a disease related to leukemia, in the winter of 1995.”
“The oncologists and hematologists will not be able to use ESA for myelodysplasia or myeloid cancers.”
“Carl Sagan died 10 years ago today, on December 20, 1996, after a long battle with myelodysplasia.”
“They do, however, have an increased risk of developing acute myelogenous leukemia or myelodysplasia, a bone marrow disorder.”
“* Treatment-related acute myeloid leukemia (AML) or myelodysplasia has occurred in patients given anthracyclines and/or cyclophosphamide, including use with Taxotere® in adjuvant therapy of breast cancer”
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