operon

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It was largely the work of François Jacob and Jacques Monod and led, at the beginning of the 1960s, to the identification of messenger RNA as the mediator between genes and proteins, and to the description of a regulatory model of gene activation, the so called operon-model, in which two classes of genes became distinguished: One class was that of structural genes.

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Definitions (2)

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  1. noun A unit of genetic material that functions in a coordinated manner by means of an operator, a promoter, and one or more structural genes that are transcribed together.

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Examples

  • It was largely the work of François Jacob and Jacques Monod and led, at the beginning of the 1960s, to the identification of messenger RNA as the mediator between genes and proteins, and to the description of a regulatory model of gene activation, the so called operon-model, in which two classes of genes became distinguished: One class was that of structural genes. —  Gene
  • Fisher et.al. have demonstrated that under acidic conditions, a 4-5 fold upregulation of the mymA operon is accompanied by a two fold reduction in the expression of FAS-II operon associated genes —  PLoS ONE Alerts: New Articles
  • Xia L, Zuber P (1991) Transcription initiation region of the srfA operon which is controlled by the comP-comA signal transduction system in —  PLoS ONE Alerts: New Articles
  • Transcription in this operon is positively regulated by the cAMP-receptor protein (CRP) [ —  Citizendium, the Citizens' Compendium - Recent changes [en]
 

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