platelet

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FOXO (Forkhead box O) transcription factors induce cell growth arrest and apoptosis, which can be prevented by FOXO phosphorylation by AKT in response to growth factors such as platelet-derived growth factors (PDGF) and insulin-like growth factor I (IGF-I).

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Definitions (4)

Toggle American Heritage definitions American Heritage Dictionary (1)

  1. noun A minute, nonnucleated, disklike cytoplasmic body found in the blood plasma of mammals that is derived from a megakaryocyte and functions to promote blood clotting. Also called blood platelet, thrombocyte.

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Examples (38)

  • BACKGROUND: We determined whether whole blood impedance aggregometry using the Multiplate detects the effects of antiplatelet drugs as reliably as does classical light transmission aggregometry (LTA) or the platelet function analyzer PFA-100 (R). —  CiteULike: Everyone's library
  • Among hospitalized patients with cancer, receipt of either a red blood cell transfusion or a platelet transfusion appears to increase the risk of blood clots.
  • Ginkgolides are structurally unique constituents of Ginkgo biloba extracts and are known antagonists of the platelet-activating factor (PAF) receptor. —  CiteULike: Everyone's library
  • FOXO (Forkhead box O) transcription factors induce cell growth arrest and apoptosis, which can be prevented by FOXO phosphorylation by AKT in response to growth factors such as platelet-derived growth factors (PDGF) and insulin-like growth factor I (IGF-I). —  Journal of Biological Chemistry current issue
  • Nowadays there is also much interest in monitoring the efficacy of anti-platelet therapy and measuring platelet hyper-function. —  CiteULike: Everyone's library
 

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/ˈpleɪtlɛt/
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