from The American Heritage® Dictionary of the English Language, 4th Edition
- n. A nonnarcotic analgesic drug, C22H29NO2.
from Wiktionary, Creative Commons Attribution/Share-Alike License
- n. Dextropropoxyphene.
from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.
- n. a mildly narcotic analgesic drug (trade name Darvon) related to methadone but less addictive
Companies manufacturing generic versions of the drug, known as propoxyphene, will also removing their products, the FDA said.
Overdose Warning for Pain Drug Propoxyphene propoxyphene, which is sold generically and under the brand names Darvon and Darvocet.
Darvocet and their generic cousins, but is letting them stay on the market. announced several actions Tuesday to reduce the risk of overdose in patients using pain medications that contain propoxyphene, which is considered a weak pain reliever but is commonly prescribed.
The prescription-only drug also is known by its generic name propoxyphene
And earlier this month, the FDA ordered manufacturers of pain medications containing an ingredient called propoxyphene to strengthen the drug labels, including a boxed warning that emphasizes the potential for overdose in people taking these pain medications, which include the older pain drugs Darvon and Darvocet.
Seizures can occur in patients who have used benzodiazepines for the treatment of seizure disorders, in patients who are physically dependent on benzodiazepines or in patients who have ingested drugs (e.g., cyclic antidepressants, cocaine, lithium, methylxanthines, isoniazid, propoxyphene, monoamine oxidase inhibitors, bupropion HCl and cyclosporine) that place them at risk for the development of seizures. 5
While the agency went against that advice and allowed propoxyphene to remain on the market, it also directed the manufacturer, Xanodyne, to conduct the study that found the heart-rhythm dangers.
The Food and Drug Administration said today that the painkiller propoxyphene is being withdrawn from the market because it has been linked to a potentially deadly heart-rhythm abnormality, even when taken at recommended doses.
The FDA noted that propoxyphene had been associated with more than 2,100 reports of serious problems — including suicide, overdose, cardiac arrest, and death — since it was first launched in 1957.
Our Best Buy Drugs report on opioid pain medicines has long recommended against using products containing propoxyphene because of safety concerns.
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