from The American Heritage® Dictionary of the English Language, 5th Edition.

  • noun A polypeptide hormone that is produced in the duodenum, especially on contact with acid, and that inhibits gastric secretion of acid and stimulates secretion of bile, insulin, and pancreatic digestive enzymes.

from The Century Dictionary.

  • noun A peculiar substance which is derived from the mucous membrane of the intestinal tract and, after absorption into the blood-current, stimulates the pancreas and possibly also the salivary glands to secretion. The substance is supposedly present in the epithelial cells of the intestinal mucosa in an inactive form which is termed prosecretin. Of its chemical nature nothing is known, but it appears certain that secretin is not a ferment.

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun biochemistry A peptide hormone, secreted by the duodenum, that serves to regulate its acidity

from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.

  • noun a gastrointestinal hormone that stimulates the secretion of water and bicarbonate from the pancreas and bile ducts whenever the stomach empties too much acid into the small intestine


from The American Heritage® Dictionary of the English Language, 4th Edition

[secret(ion) + –in.]


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  • To help make sense of available research, the federal Agency for Healthcare Research and Quality commissioned scientists to examine three types of treatment: behavioral therapy, antipsychotic and antidepressant drugs, and an enzyme called secretin.

    Research: Autism treatments fall short 2011

  • This process is called secretin 'the lime; coral insects do the same, and, as many of the islands of the south seas are made by coral insects, you may guess that a considerable lot of lime is made away with.

    Sunk at Sea 1859

  • He was the first child in the UK to trial injections of a synthetic hormone called secretin.

    Evening Standard - Home Sophie Goodchild 2011

  • One of the three reviews also looked at secretin, which is used to alleviate gastrointestinal issues that are found in some children diagnosed with autism.

    ABC News: Top Stories 2011

  • Substances such as secretin are in fact sometimes referred to rather informally as "chemical messengers."

    The Human Brain Asimov, Isaac 1963

  • The influx of acid from the stomach suffices to break the prosecretin molecule into smaller fragments, and these fragments " secretin " diffuse out into the bloodstream.

    The Human Brain Asimov, Isaac 1963

  • Parents felt just as strongly about secretin and MMR at one time as they do today about mercury.

    Op-eds on vaccines by Paul Offit, MD 2010

  • It is unclear how many doctors and families advocate its use, but a 1998 case report of three children stirred excitement by suggesting the children showed social, cognitive and communication improvement after receiving two infusions of secretin.

    Autism Treatments Scrutinized in Study Shirley S. Wang 2011

  • In the past 10 years, however, a number of high-quality studies showed there was no effect of secretin on autism symptoms, a conclusion borne out by researchers from Vanderbilt University who reviewed these studies in aggregate.

    Autism Treatments Scrutinized in Study Shirley S. Wang 2011

  • Before that, secretin, a small protein secreted by the intestine, was proposed as a cure; many parents traveled hundreds of miles and spent thousands of dollars for secretin injections.

    Op-eds on vaccines by Paul Offit, MD 2010


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  • "Of its chemical nature nothing is known"...sshhh!

    July 29, 2022