sialic

• The nonciliated cell tropism of recent human H3N2 viruses reflects a preference for the sialic acid linkages displayed on these cell types and suggests a drift in the receptor binding phenotype of the H3 hemagglutinin protein as it evolves in humans away from its avian virus precursor. —  CiteULike: Everyone's library
• When NEU1 strips the sialic acids off LAMP-1, this protein is rapidly turned over so that its total amount is reduced.
• In a series of experiments, d'Azzo's team discovered that the way NEU1 regulates the pool of lysosomes destined for lysosomal exocytosis is by cutting off a sugar called sialic acid from a structural protein of the lysosomal membrane, known as LAMP-1.
• Interestingly that sialic acid is present at high concentrations in blood DANA increased the VHH binding to recombinant TcTS. —  PLoS ONE Alerts: New Articles
• Trans-sialidase activity was measured as the transfer of sialic acid from 1 mM sialyl-α - (2-3) - lactose (Sigma) to 12 µM [D-glucose-1 - —  PLoS ONE Alerts: New Articles

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