toxicokinetics

Frequently the terms toxicokinetics, pharmacokinetics, or disposition may be found in the literature to have the same meaning.

Toxicokinetics 2007

'toxicokinetics', Positive results in one or more mutagenicity has been outlined in an ICH guideline (Federal assays do not necessarily translate into human Register, 1 March 1995).

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However, metabolism is sometimes not specific for the transformation process but may include other phases of toxicokinetics.

Biotransformation 2008

Disposition is often used in place of toxicokinetics to describe the time-course of movement of chemicals through the body (that is, how does the body dispose of a xenobiotic?).

Toxicokinetics 2007

Examples of how toxicokinetics of a substance can influence its toxicity:

Toxicokinetics 2007

Moreover, the species differences in toxicokinetics, whereby BPA as parent compound is less bioavailable in humans than in rodents, raise considerable doubts about the relevance of any low-dose observations in rodents for humans.

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The toxicokinetics literature is extensive and a listing of all the excellent toxicology and toxicokinetics textbooks is beyond the scope of this tutorial.

Toxicokinetics 2007

The potency of a chemical, or how toxic it is, depends upon its movement through the body to the target site (toxicokinetics); its ability to interact with the body to cause harm (toxicodynamics); and the dose the body receives (exposure level), which is in turn modified by the toxicokinetics and toxicodynamics of the chemical.

Toxicology 2007

This glossary contains definitions of 355 terms frequently used in the multidisciplinary field of toxicokinetics.

108959041568439494 « ResourceShelf 2004

The glossary is compiled primarily for chemists who find themselves currently working in toxicology and requiring a knowledge of the expressions used in toxicokinetics, especially in relation to hazard and risk assessment.

108959041568439494 « ResourceShelf 2004