antiangiogenic love


from The American Heritage® Dictionary of the English Language, 4th Edition

  • adj. Of or relating to a naturally occurring substance, drug, or other compound that can destroy or interfere with the fine network of blood vessels needed by tumors to grow and metastasize.

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • adj. That inhibits angiogenesis (especially when used to combat cancer).
  • n. Any drug of this kind.


from Wiktionary, Creative Commons Attribution/Share-Alike License

anti- +‎ angiogenic


  • The virus also carried an antiangiogenic gene that inhibits blood-vessel growth in tumors.

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  • Increasing the intake of these substances may prove to have antiangiogenic benefits, such as cancer prevention and weight reduction.

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  • Two new antiangiogenic drugs, Lucentis and Macugen, effectively treat, and can, in some cases, even reverse vision loss.

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  • “While the natural source may use this compound for defense or signaling, other scientists have shown this compound as having potential for treatment of cancer due to its antiangiogenic activity and efficacy against human breast cancer cell lines,” Movassaghi said.

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  • He thought treatment with antiangiogenic drugs -- ones that aim to cut off a tumor's blood supply -- might nip the early disease in the bud.

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  • These findings support the role of angiogenesis in ovarian cancer progression and the use of antiangiogenic therapy.

    BioMed Central - Latest articles

  • Zhou Z, Nemeth JA, Chen Q, Sharp C, et al. (2004) CNTO 95, a fully human monoclonal antibody that inhibits alphav integrins, has antitumor and antiangiogenic activity in vivo.

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  • Notably, the antiangiogenic effect of bevacizumab (anti-VEGF antibody) requires normalization of VEGFR1 and VEGFR2 levels in human squamous-cell carcinomas vascularized with human blood vessels in immunodeficient mice.

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  • This is thus the first study describing an antiangiogenic effect for snake venom PLA

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  • Integrins are essential in the complex multistep process of angiogenesis and are thus attractive targets for the development of antiangiogenic therapies.

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