Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. A eukaryotic nucleolar phosphoprotein that is involved in the synthesis and maturation of ribosomes

Etymologies

Sorry, no etymologies found.

Examples

  • It binds to the protein nucleolin, which is found on the surface of cancer cells.

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  • Finally, we find in many ova (but not in all) a still further point within the germinal spot, a "nucleolin," which goes by the name of the germinal point.

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  • When AS1411 binds to nucleolin on cancer cells, it is internalised and causes apoptosis through interference with various functions of nucleolin.

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  • AS1411 binds to nucleolin, a protein expressed in the nucleus of all cells but which in cancer cells is also found on the cell surface.

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  • * #3642: AS1411 causes a specific increase in levels of cell surface nucleolin in responsive cell lines (Teng et al.)

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  • * #4450 A new paradigm for AS1411 activity: Uptake by macropinocytosis and induction of macropinocytosis by a nucleolin-dependent mechanism (Reyes-Reyes et al.)

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  • FLIP; hnRNP K; nucleolin; prognosis; nasopharyngeal carcinoma

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  • Through iTRAQ-mass spectrometric identification of proteins differentially associated with the poly (C) element or its mutant, nucleolin was determined to be a cofactor of hnRNP K for

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  • Taken together, these findings indicate that FLIP expression is transcriptionally regulated by hnRNP K and nucleolin, and may be a potential prognostic and therapeutic marker for NPC.

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  • EP-302 is a targeted membrane-disrupting peptide designed to selectively kill cells that express nucleolin on their surface.

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