from The American Heritage® Dictionary of the English Language, 5th Edition.
- noun A usually benign tumor of the adrenal medulla or the sympathetic nervous system in which the affected cells secrete increased amounts of epinephrine or norepinephrine.
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun medicine A
neuroendocrine tumourof the medullaof the adrenal glands
from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.
- noun a vascular tumor of the adrenal gland; hypersecretion of epinephrine results in intermittent or sustained hypertension
from The American Heritage® Dictionary of the English Language, 4th Edition
The doctor told my brother and me he had to remove the whole adrenal gland in addition to the tumor -- a pheochromocytoma, which is fairly rare.
It is important to distinguish whether a patient with MEN2 has a pheochromocytoma because patients with undiagnosed tumors can develop malignant hypertension (a severe elevation of the blood pressure) following treatment with general anesthesia.
Patients with MEN2 who have no symptoms should be screened annually for the presence of a pheochromocytoma.
This screening can be done through the use of specific blood tests which assess for elevations in the levels of catecholamines, chemicals released by pheochromocytoma tumor cells.
Any abnormal examination findings or test results should be followed by specific radiology evaluations such as MRI to look for the presence of a pheochromocytoma tumor.
Patients with pheochromocytoma who require surgery should undergo evaluation by an anesthesiologist and may require treatment with special medications to prevent the onset of malignant hypertension.
Other tests showed similar results, the researchers said, notably in 14 patients with pheochromocytoma, a rare tumor of the adrenal glands, and paraganglioma, another rare tumor.
FMTC is diagnosed in families with four or more cases of MTC in the absence of pheochromocytoma or parathyroid adenoma or hyperplasia, and is considered a variant of MEN2A.
It is important to note that these symptoms are not definite signs of MTC, pheochromocytoma or hyperparathyroidism.
Familial medullary thyroid cancer (FMTC) is associated with an increased riskof developing medullary thyroid cancer (MTC) in early or middle adulthood, but it is not associated with the development of pheochromocytoma or parathyroid disease.