American Heritage® Dictionary of the English Language, Fourth Edition
- A trademark used for the drug pentylenetetrazol.
- n. a drug used as a circulatory and respiratory stimulant; larger doses cause convulsions in shock therapy; Metrazol is a trademark
“But in the larger world, Metrazol therapy joined the insulin treatment to offer hope where there had previously been none.”
“First we Cardiazolize them Cardiazol was the British version of Metrazol, then we insulinate them, and now we are proceeding to electrocute them.”
“Meduna treated five more patients with similar results, and by the end of 1934 had found a better drug than camphor: Metrazol, a newly marketed cardiac drug that at high doses caused seizures.”
“And so it was that doctors turned to shocking therapies - insulin shock therapy, Metrazol shock therapy, electroconvulsive shock therapy, and of course, most shocking of all - the lobotomy.”
“Metrazol had a lower mortality level, but ensuing convulsions led to various fractures and respiratory problems.”
“There is no solid evidence that lecithin, choline, Metrazol, hyperbaric oxygen, vasopressin, or procaine is effective in reducing cognitive dysfunction or improving the general health of patients with primary degenerative dementia 814.”
“Metrazol (60 mg/kg body weight) is the maximum toxic dose which induced convulsions in mice with minimum mortality rate, whereas 70 mg/kg body weight is the minimum lethal dose causing 99% mortality of the mice.”
“Paxil, Zoloft, Prozac, Tofranil, Wellbutrin, Elavil, Metrazol in combination with unilateral ECT (during a two-week voluntary in-patient course of treatment at a regional Mood Disorders clinic),”
“So I ran gerbils through a maze, timed them, and then injected them with Metrazol (the brand name for pentylenetetrazol, a central nervous system stimulant), and then ran them through the maze again.”
“Metrazol electricity hydrotherapy psycho - therapy occupational therapy pingpong & poem”
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