American Heritage® Dictionary of the English Language, Fourth Edition
- n. A drug, C5H4N4O, used to treat gout because it inhibits the synthesis of uric acid.
- n. a drug (trade name Zyloprim) used to treat gout and other conditions in which there is an excessive buildup of uric acid
- allo- + purine + -ol (Wiktionary)
- allo- + purin(e) + -ol2. (American Heritage® Dictionary of the English Language, Fourth Edition)
“Patients can take drugs, particularly one called allopurinol, to reduce the level of uric acid and eventually eliminate symptoms of gout.”
“Despite afflicting an estimated two to six million Americans, the standard approach for treating gout over the last 40 years has been a drug called allopurinol, which inhibits an enzyme that produces uric acid.”
“For many years, the most common drug used to treat gout was allopurinol, which is generally safe and effective, but has been known to cause life-threatening rashes in rare cases.”
“Or your doctor may suggest another drug, such as allopurinol (Zyloprim) or hydrochlorothiazide (Esidrix, Hydro-DIURIL), that prevents stones in other ways.”
“Azathioprine, a drug that prevents rejection of transplanted organs and allopurinol which is used in the treatment of gout were developed in 1957 and 1963, respectively.”
“He said studies have shown that increasing the dose of a drug such as allopurinol does not have a great impact on serum urate, but by combining allopurinol with drugs such as benzbromarone, a greater reduction in urate levels can be achieved.”
“Besides a low purine diet, preventive medicines such as allopurinol, febuxostat, and probenecid can be used to prevent recurrences.”
“In addition, because increasing the excretion of serum uric acid is additive to the effects of drugs such as allopurinol that decrease the production of uric acid, RDEA594 in combination with such drugs has the potential to treat the significant portion of the gout population that is not adequately treated with existing therapies.”
“The records Randy received were flimsy, but he noticed that the patient was on allopurinol, a treatment for gout.”
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