American Heritage® Dictionary of the English Language, Fourth Edition
- n. Reversion of cells to an immature or a less differentiated form, as occurs in most malignant tumors.
Century Dictionary and Cyclopedia
- n. In pathology, the sum of the morphological, structural, chemical, and other alterations which cells undergo when assuming the characteristics of malignancy.
- n. Same as anaplasis.
GNU Webster's 1913
- n. loss of structural differentiation within a cell or group of cells often with increased capacity for multiplication, as in a malignant tumor.
- n. loss of structural differentiation within a cell or group of cells often with increased capacity for multiplication, as in a malignant tumor
- ana- + -plasia (Wiktionary)
“In MB, over-expression of c-MYC has been shown to cause anaplasia and correlate with unfavorable prognosis.”
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