from Wiktionary, Creative Commons Attribution/Share-Alike License
- adj. Acting to prevent epilepic seizures
- n. A drug which acts to prevent epileptic seizures
from the GNU version of the Collaborative International Dictionary of English
- Same as antepileptic.
from The Century Dictionary and Cyclopedia
- n. Same as antepileptic.
from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.
- n. a drug used to treat or prevent convulsions (as in epilepsy)
Availability of investigational antiepileptic medications.
In 2008, the FDA warned that patients on all antiepileptic drugs should be "monitored for the emergence or worsening of depression, suicidal thoughts or behavior, or any unusual changes in mood or behavior," and warnings on drug labels were soon required.
But this month FDA issued a warning that pregnant women who take the antiepileptic drug Topamax are 20 times as likely to have their babies develop cleft lip and cleft palate as they would otherwise be, says Reuters.
That compared to a rate of 0.38% to 0.55% in infants exposed to other antiepileptic drugs.
Mild antiepileptic drugs, even if they do alter development, will still cause this child to thrive far more than if the kid went untreated.
The diuretics were contaminated with bacteria; the antiepileptic drugs were contaminated with fungi, and one patient died because of taking those drugs; the antihypertensive drugs and the antidiabetic drugs were mixed.
A recent FDA Information for Healthcare Professionals sheet 12/12/2007, described an increased risk of SJS/TEN with another antiepileptic drug, carbamazepine, in Asian ancestry patients with the HLA-B*1502 allele.
While stating that patients and doctors should carefully weigh the benefits of the drugs against the risks, the agency is urging doctors to “closely monitor all patients currently taking or starting any antiepileptic drug for notable changes in behavior that could indicate the emergence or worsening of suicidal thoughts or behavior or depression.”
This time the culprits are antiepileptic drugs -- medications used to control seizures.
The FDA said it would be working with manufacturers of the antiepileptic drugs to include the new information in product labeling.
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