Definitions

from The American Heritage® Dictionary of the English Language, 4th Edition

  • adj. Of or relating to a nucleotide sequence that is complementary to a sequence of messenger RNA. When antisense DNA or RNA is added to a cell, it binds to a specific messenger RNA molecule and inactivates it.

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. A molecule which interacts with a complementary strand of nucleic acids, so as to suppress its transcription.

Etymologies

anti- +‎ sense (Wiktionary)

Examples

  • The researchers also suppressed CPE-delta N in mice using an experimental approach called antisense and found tumors implanted into the animals did not spread.

    Yahoo! News: Business - Opinion

  • Isis Pharmaceuticals, Inc. engages in the discovery and development of a new class of drugs called antisense drugs using antisense technology, a novel drug discovery platform to generate

    StreetInsider.com News Articles

  • Working with a class of compounds known as antisense phosphorodiamidate morpholino oligomers, or PMOs, scientists conducted studies in which nine rhesus monkeys were challenged with lethal Ebola virus, reports

    Daily News & Analysis

  • Working with a class of compounds known as antisense phosphorodiamidate morpholino oligomers, or PMOs, scientists first performed a series of studies with mouse and guinea pig models of Ebola to screen various chemical variations.

    PhysOrg.com - latest science and technology news stories

  • Simard's team blocked this gene in mice and rats using gene-blocking therapy called antisense and showed that after a spinal cord injury, the damage and effects were much less without ABCC8.

    FOXNews.com

  • Researchers demonstrate efficacy of antisense therapy for spinal muscular atrophy disease spinal muscular atrophy (SMA) might soon be treated with tiny, chemically modified pieces of RNA called antisense oligonucleotides (ASOs).

    WN.com - Articles related to Length of biological marker linked to cancer

  • In the study, Simard and his colleagues gave a drug called antisense oligodeoxynucleotide

    Medlogs - Recent stories

  • Unlike traditional gene therapy, which attempts to replace a mutated gene with a functional copy, exon skipping relies on a variation of a technique called antisense, in which short synthetic DNA or RNA molecules are designed to bind to a region of DNA or RNA and block its function.

    Technology Review RSS Feeds

  • DIG-labelled antisense RNA probes synthesis, samples fixation and in situ hybridisation were carried out as previously described

    PLoS ONE Alerts: New Articles

  • If a gene is read forwards - called 'sense' transcription - the protein is generated in the normal way, but if the other, complementary strand is transcribed - called antisense - no protein is made.

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