from The American Heritage® Dictionary of the English Language, 4th Edition
- n. A deposit or degenerative accumulation of lipid-containing plaques on the innermost layer of the wall of an artery.
from Wiktionary, Creative Commons Attribution/Share-Alike License
- n. An abnormal fatty deposit which develops within the walls of arteries.
from the GNU version of the Collaborative International Dictionary of English
- n. An encysted tumor containing curdy matter.
- n. A disease characterized by thickening and fatty degeneration of the inner coat of the arteries.
from The Century Dictionary and Cyclopedia
- n. A name given to various kinds of encysted tumors, the contents of which have the appearance of bread-sauce.
- n. The formation of thickened patches of the inner coat of an artery (much more rarely of a vein), constituting flattened cavities which contain a pasty mass exhibiting fat-globules, fatty acid crystals, cholesterin, more or less calcareous matter, etc. Also atherome.
from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.
- n. a fatty deposit in the intima (inner lining) of an artery; can obstruct blood flow
Although the primary endpoint (change in percent atheroma volume) was not different between rimonabant and placebo, other measures of atherosclerosis appeared to change favourably.
That seems a rather unscientific conclusion, given that they observed zero effect on the most important measurable quantity clinical events, and a small effect on atheroma volume, even in the face of significant modification of lipid parameters resulting from statin therapy.
Second, reading the study carefully one finds that what the authors call the PAV (percent atheroma volume) actually increases with statin therapy (This is a measurement of the amount of the vascular wall that is composed of atheroma).
Somewhat more interesting is the following: “Substantial atheroma regression (5 percent or more reduction in atheroma volume) was observed in patients with levels of LDL-C less than the mean (87.5 milligrams per deciliter) during treatment and percentage increases of HDL-C greater than the mean (7.5 percent).”
Aggressive lipid-lowering therapy and regression of coronary atheroma.
There was a mild coronary atheroma and slight mitral valve edge thickening.
Zillner attributed this circumstance to the small size of the wound, atheroma and degeneration of the aorta and slight retraction of the inner coat, together with a possible plugging of the pericardial opening.
It has been assigned as one of the causes of early atheroma and of angina pectoris.
Such dilatations are usually due to chronic endarteritis and atheroma.
Chronic endarteritis is fruitful in the production of thrombus and atheroma.
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