heterozygosity

• “There is also an unusual phenomenon called loss of heterozygosity (LOH) whichis described below.”

  Genetic defect, recessive, dominant, sporadic, LOH

• “This event is called “loss of heterozygosity” and is not inherited.”

  Genetic defect, recessive, dominant, sporadic, LOH

• “Outbreeding groups of organisms with high degrees of heterozygosity tend to be fitter than inbred groups.”

  Modern humans may have inherited some Neanderthal genes - The Panda's Thumb

• “Sickle cell anemia is caused by having two copies of the sickle cell allele and is a necessary by-product of strong selection for heterozygosity in malaria-ridden regions.”

  A Patriarchy Complex?, Arnold Kling | EconLog | Library of Economics and Liberty

• “So, in order for this model to apply to homosexuality you'd have to show that there's some sort of massive fitness benefit on the level of sickle heterozygosity that causes homosexuality to persist at levels 1%, which more than makes up for the fitness costs of preferential homosexuality.”

  A Patriarchy Complex?, Arnold Kling | EconLog | Library of Economics and Liberty

• “I would be interested to see a more in-depth explanation of “lethal” heterozygosity levels and the various ways later researchers were able to account for them.”

  Haldane's non-dilemma - The Panda's Thumb

• “Kimura Kimura, 1968 used the heterozygosity problem to advance the neutral theory.”

  Haldane's non-dilemma - The Panda's Thumb

• “Since the alleles have no effect on fitness, a very large number of allelic variants can be in the population and not reduce its fitness, thus solving the heterozygosity problem.”

  Haldane's non-dilemma - The Panda's Thumb

• “The authors concluded that heterozygosity explained only a very small amount of variation in symmetry.”

  Academic Dishonesty

• “One important effect of random drift is to decrease the degree of heterozygosity in a population over time.”

  Population Genetics

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