Examples
“I reasoned that the aspartame could have altered the catecholamine/indoleamine balance and thus account for her clinical difficulties.”
New York Psychiatrist Exhorts FDA to Rescind Artificial Sweetener Aspartame Approval
“My hypothesis in this study was that since aspartame led to an increase in norepinephrine precursors, coupled with a simultaneous decrease in serotonin precursors, the potential alteration in central nervous system catecholamine/indoleamine balance would pose a special challenge for patients with a mood disorder.”
“A role for inducible nitric oxide (iNOS), programmed death ligand-1 (PD-L1) and prostaglandin E2 (PGE2), but not indoleamine 2,3-dioxigenase (IDO), in the T cell inhibition was demonstrated.”
“In August we initiated a new clinical program in oncology with Incyte 24360, a selective orally available inhibitor of indoleamine 2, 3-dioxygenase”
Incyte CEO Discusses Q3 2010 Results - Earnings Call Transcript -- Seeking Alpha
“Many human tumors express indoleamine 2,3-dioxygenase (IDO), an enzyme which mediates an immune-escape in several cancer types.”
“The University of Illinois scientists identified the enzyme IDO (indoleamine 2,3 dioxygenase) as a molecular switch that induces depressive symptoms in some cases.”
“But high doses block inflammation by increasing expression of the enzyme indoleamine 2,3 dioxygenase, or IDO, an immunosuppressor, the researchers say.”
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