from The American Heritage® Dictionary of the English Language, 4th Edition
- n. A polymer that consists of two, three, or four monomers.
from Wiktionary, Creative Commons Attribution/Share-Alike License
- n. A compound intermediate between a monomer and a polymer, normally having a specified number of units between about five and a hundred.
from the GNU version of the Collaborative International Dictionary of English
- n. A molecule composed of a small number of linked monomer units; a short polymer; -- compounds called oligomers have less than one hundred monomer units and usually less than thirty. Oligomers of increasing length are called dimer, trimer, tetramer, pentamer, hexamer, heptamer, octamer, nonamer, decamer, etc. In colloquial laboratory jargon, they may also be referred to as nine-mer, ten-mer, eleven-mer, twelve-mer, etc., especially for oligomers of greater than eight units.
I concluded that H3 and H4 must form a dimer, and I thought I might crystallize and solve the structure of this unique histone oligomer.
The rate of such changes and the mean length of such oligomers are dependent on the thermodynamic context (in the extreme case, an ice crystal may be considered as a single such oligomer, the crystal structure being dependent on the fixed, strong hydrogen bonds).
K172 indicated that the 392-amino acid-residue-long bacterial enzyme 6-aminohexanoic acid linear oligomer hydrolase involved in degradation of nylon oligomers is specified by an alternative open reading frame of the preexisted coding sequence that originally specified a 472-residue-long arginine-rich protein. sanjait
I started thinking about their problem and proposed an idea of my own which they ended up calling oligomer restriction.
The oligomer restriction method also relied on the fact that the target of interest contained a restriction site polymorphism, which kept it from being universally applicable to just any point mutation.
AVI's proprietary, intrinsically charge-neutral, phosphorodiamidate morpholino oligomer PMO
AVI BioPharma and Leading Researchers at Karolinska Institutet Form Collaboration to Identify RNA-Based Therapeutic Candidates for Treatment of Extensively Drug-Resistant Tuberculosis (XDR-TB) - Yahoo! Finance
AVI-7100 employs the Company's patented PMOplus™ technology that selectively introduces positive charges to a phosphorodiamidate morpholino oligomer PMO backbone to improve selective interaction between the drug and its target.
This leads to a simple analytical form for the ligand-dependent free energy per ligand-binding subunit, and KI are the ligand dissociation constants for the active and inactive states of the oligomer, respectively.
An important assumption of the model is that the ligand dissociation constant for binding sites depends on the activity state of the oligomer.
Dr. Charles Glabe, an oligomer expert and a member of the Cure Alzheimer Fund research consortium, is also a co-author of the paper.
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