Definitions
American Heritage® Dictionary of the English Language, Fourth Edition
- n. A drug that suppresses gastric acid secretion and is used for the treatment of duodenal and gastric ulcers and gastroesophageal reflux disease.
Wiktionary
- n. pharmacology A benzimidazole, C17H19N3O3S, which is a proton pump inhibitor, taken to prevent the secretion of gastric acid.
WordNet 3.0
- n. antacid (trade name Prilosec) that suppresses acid secretion in the stomach
Etymologies
- Origin uncertain; the OED suggests o(xy-) + me(thyl-) + p(y)r(idine) + (imid)az(ole) + (ind)ole. (Wiktionary)
- Perhaps o(xy)- + me(thyl) + -prazole, antiulcer agent suff. (ultimately from (benzimid)azole). (American Heritage® Dictionary of the English Language, Fourth Edition)
Examples
“My husband spent a small fortune on antacids for his heartburn until he started taking a proton pump inhibitor PPI called omeprazole a few years ago.”
Consumer Reports: Popular heartburn drugs linked to increased risk of fractures
“My husband spent a small fortune on antacids for his heartburn until he started taking a proton pump inhibitor (PPI) called omeprazole a few years ago.”
Consumer Reports: Popular heartburn drugs linked to increased risk of fractures
“AstraZenica, the international pharmaceutical company worth $46.8 billion, began selling a drug called omeprazole in 1989 under the brand name Prilosec.”
“Those drugs included either a proton-pump inhibitor (PPI), such as omeprazole, esomeprazole (Nexium), and lansoprazole (Prevacid and generic); or an H2-blocker, such as famotidine (Pepcid and generic).”
Consumer Reports: Time to take a break from heartburn drugs?
“If your doctor says you need aspirin, but you have a history of stomach bleeding, ask about adding a stomach-protecting drug such as omeprazole (Prilosec and generic).”
“If your doctor says you need aspirin, but you have a history of stomach bleeding, ask about adding a stomach-protecting drug such as omeprazole Prilosec and generic.”
“Many drugs are used for the treatment of GERD such as omeprazole (a proton pump inhibitor) which is a widely used antiulcer drug demonstrated to protect against esophageal mucosal injury.”
“SAN FRANCISCO, CA - SEPTEMER 24, 2009 - Results from a late breaking clinical trial called COGENT demonstrate that the combination of giving patients clopidogrel, a blood thinner commonly prescribed to patients with cardiovascular disease, and stomach medicines such as omeprazole, known as proton pump inhibitors (PPIs), did not lead to adverse events, as some prior studies had suggested.”
“Many drugs, including certain proton pump inhibitors such as omeprazole, also inhibit CYP2C19 (iii).”
“Treatments include laparoscopic surgical fixes and the use of proton pump inhibitor (PPI) drugs such as Nexium (esomeprazole), Prilosec (omeprazole) and Prevacid (lansoprazole).”
USA Today: Study: Pills, surgery both effective for chronic reflux
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