Definitions

from The American Heritage® Dictionary of the English Language, 5th Edition.

  • noun A degradation product of penicillin, C5H11NO2S, that is used as a chelating agent and in the treatment of rheumatoid arthritis, Wilson's disease, and lead poisoning.

from the GNU version of the Collaborative International Dictionary of English.

  • noun (Chem., Med.) A substance (C5H11NO2S) which is a degradation product of the penicillins. Chemically it is 3-mercapto-D-valine. It has chelating properties and is used in medicine as an antirheumatic and to chelate copper in cases of hepatolenticular degeneration (Wilson's disease).

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun chemistry a breakdown product of penicillin used as a chelating drug to treat poisoning by heavy metals etc

from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.

  • noun a drug (trade name Cuprimine) used to treat heavy metal poisoning and Wilson's disease and severe arthritis

Etymologies

from The American Heritage® Dictionary of the English Language, 4th Edition

[penicill(in) + –amine.]

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Examples

  • Enter d-penicillamine, a drug for rheumatoid arthritis and adults with a rare genetic disorder.

    Pursuing a Cure 2007

  • Michael Shannon has used a drug called d-penicillamine to treat children with lead poisoning.

    Pursuing a Cure 2007

  • After hospitalization lowered her levels, Dr. Shannon prescribed d-penicillamine to try to get the lead down even further.

    Pursuing a Cure 2007

  • Among parents who have used d-penicillamine, no one questions the need for a palatable recipe.

    Pursuing a Cure 2007

  • In his office at Children's Hospital Boston recently, Dr. Shannon points to the table where he sits with parents after a child has completed the d-penicillamine regimen.

    Pursuing a Cure 2007

  • And while d-penicillamine has potentially serious side effects at adult doses, at the low doses given to the children, he says, there were milder reported events, such as rashes and stomach upset.

    Pursuing a Cure 2007

  • He says he knows of at least a dozen compounds that, like d-penicillamine, could be reformulated for FDA approval for pediatric use with investments of $2 million to $8 million.

    Pursuing a Cure 2007

  • So he and the hospital were eager to work with Tedor to develop a new, better-tasting formula for d-penicillamine that could be FDA approved for kids and thus gain wider use.

    Pursuing a Cure 2007

  • Colchicine, d-penicillamine, and order colchicine online cod in the product of professional pulmonary fibrosis: a informed preferable trial.

    Wii-volution 2010

  • After developing the blood test for Wilson disease, he worked with Dr. Irmin Sternlieb and Dr. John M. Walshe of Cambridge University in England to treat the disease by using the oral drug D-penicillamine

    news | GT | http://www.gadsdentimes.com 2009

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