Definitions
American Heritage® Dictionary of the English Language, Fourth Edition
- adj. Immunologically reactive to itself. Used of a cell or antibody.
Examples
“So far, early studies in MS populations are promising, indicating that Rituxan does lead to rapid depletion of self-reactive B cells.”
“These self-reactive T cells stimulate other immune cells to produce autoantibodies that attach to the perfectly fine, healthy cells within our body—in any organ or tissue—and cause cells to die.”
“Some of these are self-reactive (like on Elventh Hour, but without the picking up metals from their substrate part) in that they spread over the glass surface and bond with it.”
“When the immune system is regarded as essentially self-reactive and interconnected, the”
“The first T cells to be positively selected and activated in the thymus are self-reactive CD4 T cells that thus become “regulatory.””
“In other words, immune regulation in this theory is based on the reactivity of antibodies (and later lymphocytes) with their own repertoire to form a set of self-reactive, self-reflective, self-defining immune activities.”
“Burnet's theory proposed that the animal, during prenatal development, exercised a purging function of self-reactive lymphocytes”
“However, little is known about their role in autoimmune diabetes, a disease characterized by the reduction of insulin production subsequent to destruction of pancreatic β-cells by a polyclonal population of self-reactive T-cells.”
“Medullary thymic epithelial cells (mTECs), acting together with MHC class II + dendritic cells, function to negatively select thymocytes that bear high affinity self-reactive TCRs”
“This knowledge should help us identify more specific therapeutic targets that will improve the treatment of diseases resulting from self-reactive or malignant B cells.”
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