American Heritage® Dictionary of the English Language, Fourth Edition
- n. A statin, C 25H38O5, that blocks the body's synthesis of cholesterol and is administered especially to individuals at risk for heart disease.
GNU Webster's 1913
- n. a chemical substance (C25H38O5) having inhibitory activity on the enzyme HMG-CoA reductase, and used in medicine to reduce cholesterol levels in blood.
- n. an oral lipid-lowering medicine (trade name Zocor) administered to reduce blood cholesterol levels; recommended after heart attacks
- sim- (perhaps alteration of syn-, pref. indicating attachment on the same side of the plane as a double bond; see syn-) + -vastatin, statin suff.; see pravastatin. (American Heritage® Dictionary of the English Language, Fourth Edition)
“On Drugs 'Link To Muscle Injury WASHINGTON -- Federal regulators continue to receive reports of muscle injury in patients taking a combination of simvastatin, which is used in the controversial cholesterol drug Vytorin, and the heart-rhythm medication amiodarone.”
“One statin, a generic drug called simvastatin, is already available in low doses over the counter at pharmacies in Britain without a prescription, at a cost of only a few pence per pill.”
“According to an analysis of clinical trial data in America, large doses of simvastatin, which is taken in order to lower cholesterol and reduce the risk of having a heart attack, can cause muscle damage and a rare condition which induces kidney problems and may be fatal.”
“Vytorin combines in one pill two different kinds of treatments - a statin called simvastatin and a newer drug called ezetimibe, also known as Zetia - that lower LDL or "bad" cholesterol.”
“Food and drug administration said it has focused health-care vessels that the rxlist vytorin was traveling a withdrawal from the so-called simvastatin and ezetimibe in aortic stenosis (seas) shortness of a unaffected species between the cure of vytorin and an brought cream of a death of cancers.”
“That site is tracking research on supposed anti-aging compounds such as simvastatin, used to lower cholesterol, and enalapril maleate, which is used to treat hypertension.”
“The study shows that Australia has comparatively low use of cheaper generic statins such as simvastatin and pravastatin.”
“They tested their hypothesis by administering simvastatin, which is known to inhibit Rho activity, to mouse models with the Ccm2 mutations and saw that the drugs strengthened the damaged blood vessels in the mice. ”
“Medications affected by grapefruit juice include medications to treat high cholesterol, such as simvastatin (Zocor), lovastatin (Mevacor), and atorvastatin (Lipitor); for seizures, carbamazepine (Carbatrol, Tegretol); blood pressure medications, felodipine (Plendil), nifedipine (Procardia), nimodipine (Nimotop), nisoldipine”
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