Definitions
American Heritage® Dictionary of the English Language, Fourth Edition
- adj. Genetically identical or closely related, so as to allow tissue transplant; immunologically compatible: syngeneic grafts; syngeneic animals.
Wiktionary
- adj. genetics genetically identical, or sufficiently identical and immunologically compatible as to allow for transplantation
Etymologies
- From Greek sungeneia, kinship : syn-, syn- + genos, family; see genə- in Indo-European roots. (American Heritage® Dictionary of the English Language, Fourth Edition)
Examples
“Restriction of in vitro T cell-mediated cytotoxicity in lymphocytic choriomeningitis within a syngeneic and semiallogeneic system.”
“To investigate whether MSCs could provide a neuroprotective effect, we isolated and injected intravenously syngeneic MSCs into RCS rats at P30 (n = 12), at which time the retinal degeneration is at an early stage.”
“Animals received syngeneic MSCs (1×106 cells) by tail vein at an age before major photoreceptor loss.”
“To test whether pharmacological treatment of melanoma cells with IFN-γ and GGTI-298 could produce suitable cells for vaccination a murine model was used: B16F10 cell line, a poorly immunogenic and MHC-I negative melanoma of spontaneous origin, was injected in the syngeneic C57Bl/6 mice.”
“Moreover, this treatment enables the T-cell-induced reduction of tumor growth in syngeneic immunocompetent mice and enhanced levels of B16F10 specific CD8 T lymphocytes TRP-2/H-2K”
“Indeed, in vivo vaccination of syngeneic mice with pharmacologically pretreated melanoma cells induces tumor growth slowing down and reduction of pulmonary metastases implantation.”
“Again syngeneic mice were vaccinated as previously described and challenged intra-venously with 5×10”
“Vaccination of syngeneic mice with mIFN-γ+GGTI-298 pretreated B16F10 cells induces resistance to untreated tumor growth.”
“Pbγ-spz-immunized-challenged mice and from naïve-challenged mice and adoptively transferred into naïve syngeneic recipients (n = 13) that were challenged 7 days later with either 250 (n = 6) or 1000 (n = 7) infectious sporozoites.”
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