therian

• The recent release of the platypus genome has provided the first opportunity to perform comparisons between prototherian (monotreme; which appear to lack imprinting) and therian (marsupial and eutherian; which have imprinting) mammals. —  CiteULike: Everyone's library
• Results: We compared the distribution of repeat elements known to attract epigenetic silencing across the entire genome from monotremes and therian mammals particularly focusing on the orthologous imprinted regions. —  CiteULike: Everyone's library
• There was a significant accumulation of certain repeat elements within imprinted regions of therian mammals compared to the platypus. —  CiteULike: Everyone's library
• Our analyses show that the platypus has significantly fewer repeats of certain classes in the regions of the genome that have become imprinted in therian mammals. —  CiteULike: Everyone's library
• The accumulation of repeats, especially LTRs and DNA elements, in therian imprinted genes and gene clusters is coincident with, and may have been a potential driving force in, the development of mammalian genomic imprinting. —  CiteULike: Everyone's library

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