American Heritage® Dictionary of the English Language, Fourth Edition
- n. The process, operation, or method of determining the concentration of a substance in solution by adding to it a standard reagent of known concentration in carefully measured amounts until a reaction of definite and known proportion is completed, as shown by a color change or by electrical measurement, and then calculating the unknown concentration.
Century Dictionary and Cyclopedia
- n. In analytical chem., a process for ascertaining the quantity of any given constituent present in a compound by observing the quantity of a liquid of known strength (called a standard solution) necessary to convert the constituent into another form, the close of the reaction being marked by some definite phenomenon, usually a change of color or the formation of a precipitate. Also called volumetric analysis.
- n. analytical chemistry The determination of the concentration of some substance in a solution by slowly adding measured amounts of some other substance (normally using a burette) until a reaction is shown to be complete, for instance by the colour change of an indicator.
GNU Webster's 1913
- n. (Chem.) The act or process of titrating; a substance obtained by titrating.
- n. a measured amount of a solution of unknown concentration is added to a known volume of a second solution until the reaction between them is just complete; the concentration of the unknown solution (the titer) can then be calculated
- See titrate. (Wiktionary)
“ The term titration is occasionally used informally to suggest extreme precision in some sort of measurement or determination.”
“Medical doctors use the term titration to describe the process of adjusting the standard dosage of a medication up or down based on an individual patient’s reactions.”
“Both of the pivotal clinical studies enrolled adult patients with moderate to severe chronic low back pain and included open-label titration periods followed by randomized, double-blind, 12-week study periods.”
“Twenty three percent of patients discontinued due to an adverse event and 14 percent discontinued due to lack of a therapeutic effect from the open-label titration period.”
“Twelve percent of patients discontinued due to an adverse event and 21 percent discontinued due to lack of a therapeutic effect during the open-label titration period.”
“In this study, 53 percent of the patients who entered the open-label titration period were able to titrate to a tolerable and effective dose and were randomized into a 12-week, double-blind treatment period.”
“In this study, 57 percent of the patients who entered the open-label titration period were able to titrate to and tolerate the adverse effects of”
“Twelve percent of patients discontinued due to an adverse event, and 21 percent discontinued due to lack of a therapeutic effect during the open-label titration period.”
“After the expiration of four hours 20 c.c. of 10 per cent. solution of potassium iodide and 150 c.c. water are added to the contents of the bottle, and the excess of iodine titrated with N/10 sodium thiosulphate solution, the whole being well agitated during the titration, which is finished with starch paste as indicator.”
“The method of working and the conditions of the titration are the same as for the phosphate titration.”
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