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The antineoplastic agent camptothecin specifically targets DNA topoisomerase I, and several mutations have been isolated that render the enzyme camptothecin-resistant.— CiteULike: Everyone's library
VELCADE should be administered under the supervision of a physician experienced in the use of antineoplastic therapy.— Health News from Medical News Today
Azacitidine is an epigenetic compound believed to exert antineoplastic effects by causing hypomethylation of DNA and direct cytotoxicity on abnormal hematopoietic cells in the bone marrow.— Medlogs - Recent stories
In the long term, Jumonjd3 could constitute a promising target in the reprogramming of differentiated cells and in the development of antineoplastic therapies that counteract the abnormal differentiation processes at the route of tumourigenesis.— innovations-report
Our group as well have previously demonstrated that the Myc down-regulation is able to activate apoptosis and to sensitize melanoma cells to different antineoplastic agents The activation of different cell cycle checkpoints in the various cell cycle compartments functions as mechanisms of cellular surveillance and protects cells from genomic instability and deleterious effects induced by genotoxic agents— PLoS ONE Alerts: New Articles
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