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To the Editor: The study by Dr Ferlin and colleagues1 advances understanding of the genetic contributions to cryptorchidism.— JAMA current issue
In their study, the prevalence of Klinefelter syndrome, the most common genetic cause of cryptorchidism, was almost identical to that in a 1969 study in which the prevalence of Klinefelter syndrome among 600 boys with cryptorchidism was 1. 1\%.— JAMA current issue
In Reply: As Dr Gottlieb and colleagues noted, one of the main findings of our study was the frequency of detection of Klinefelter syndrome, especially in boys with persistent bilateral cryptorchidism— JAMA current issue
Prominent risk factors include undescended testis (cryptorchidism), family history, mumps and inguinal hernia— Medindia Health News
Hypogonadotropic hypogonadism typically manifests as hypoplastic external genitalia and delayed gonadal maturation, with delayed menarche and oligomenorrhea in females, and cryptorchidism and hypogonadism in males— PLoS ONE Alerts: New Articles
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