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Definitions

Century Dictionary and Cyclopedia

  1. n. Diminutive of sis, 2.

Wiktionary

  1. n. A diminutive of the female given name Cecilia.
  2. n. A diminutive of the female given name Cecilia.

WordNet 3.0

  1. n. a timid man or boy considered childish or unassertive
  2. adj. having unsuitable feminine qualities

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‘Sissy’ has been looked up 327 times, and is not a valid Scrabble word.