Definitions

from The American Heritage® Dictionary of the English Language, 4th Edition

  • n. One involved in a struggle or competition.
  • n. Physiology A contracting muscle that is resisted or counteracted by another muscle, the antagonist.
  • n. Biochemistry A drug or other chemical that can combine with a receptor on a cell to produce a physiologic reaction typical of a naturally occurring substance.

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. Someone involved in a contest or battle (as in an agon).
  • n. The muscle that contracts while the other relaxes.
  • n. A molecule that can combine with a receptor on a cell to produce a physiological reaction.

from the GNU version of the Collaborative International Dictionary of English

  • n. One who contends for the prize in public games.

from The Century Dictionary and Cyclopedia

  • n. One who contends for the prize in public games; a combatant; a champion; a dramatic actor. Also called agonister.
  • n. [capitalized] One of a violent party of Donatists in northern Africa in the fourth century.

from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.

  • n. a muscle that contracts while another relaxes
  • n. someone involved in a contest or battle (as in an agon)
  • n. the principal character in a work of fiction
  • n. (biochemistry) a drug that can combine with a receptor on a cell to produce a physiological reaction

Etymologies

Late Latin agōnista, contender, from Greek agōnistēs, from agōn, contest; see agony.
(American Heritage® Dictionary of the English Language, Fourth Edition)
From Ancient Greek ἀγωνιστής (agōnistēs, "combatant, champion") (Wiktionary)

Examples

  • In Western anatomy, these are called agonist and antagonist muscle groups, but I call them balancing muscle groups.

    The Genius of Flexibility

  • I paid homage in my review to A.J. Clark for his pioneering work in developing receptor theory, I took issue with his hypothesis that response of a tissue to an agonist is proportional to the fraction of receptors occupied by the agonist.

    Robert F. Furchgott - Autobiography

  • For example, I derived theoretical equations to illustrate how removal of the agonist from the region of the receptor by active uptake or enzymatic destruction could markedly alter the slope of

    Robert F. Furchgott - Autobiography

  • With that information, he hopes to create a peptide "agonist" - something that would enhance the activity of the CAP2B peptide and prevent the insect from leaving waste (and the parasite) on the wound.

    PhysOrg.com - latest science and technology news stories

  • An agonist is a substance that binds to a receptor.

    Alcohol and The Addictive Brain

  • Vilazodone is an anti-depressant that has two different mechanisms - it is both a selective-serotonin re-uptake inhibitor (SSRI) along the lines of other common depression treatments such as Prozac and Zoloft, while it also includes a so-called 5-HT1A receptor partial agonist, which is the mechanism in several other anti-depressant treatments on the market including buspirone.

    Philadelphia Business News - Local Philadelphia News | The Philadelphia Business Journal

  • IDC is advancing an innovative vaccine pipeline utilizing its two proprietary technologies which include GLA, a novel, synthetic, toll-like receptor 4 (TLR-4) agonist, which is a clinical stage adjuvant being developed as a component in multiple internal and partnered vaccine programs; and DC-NILV, a novel delivery vector engineered to target human dendritic cells and express target antigens and immunomodulatory elements to elicit functional and broad based immunity, which is initially being applied in cancer indications of significant unmet need.

    RedOrbit News - Technology

  • Formoterol is a long-acting beta2-agonist which is inhaled to help open the airways and last for 12 hours or more.

    NewsInferno

  • One is that its label reads: WARNING: The active ingredient in Topmax, ractopamine hydrochloride, is a beta-adrenergic agonist.

    Martha Rosenberg: Arsenic, Antibiotics and Asthma Drugs in Your Turkey?

  • A beta-2 selective agonist can be given for bronchospasm, while epinephrine should be avoided as it may precipitate dysrhythmias.

    Hydrocarbon Ingestion

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